Sunday, January 19, 2014
Nokia Lumia 2520 video review assistance
Saturday, January 18, 2014
iPad Air vs Samsung Galaxy Tab 3 10.1 video review
Friday, January 17, 2014
Best Galaxy Note 3 battery extension accessories
Thursday, January 16, 2014
Specs, pictures of the Huawei Ascend Mate 2 leak
T-Mobile Galaxy S4 Android 4.3 update begins, risky though
Wednesday, January 15, 2014
NBC app for iPad, iPhone updated
Tuesday, January 14, 2014
iPad Air dock accessory charges multiple iOS devices
Dienolone (Trenazone) Bible
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Prelude
The old tren products were very popular before the ingredient was classified as an illegal anabolic steroid. The ingredient Estra-4,9-diene-3,17-dione (tren xtreme, x-tren, etc) was actually a precursor to the compound Dienolone. The legislation didnt ban this active compound that the old tren products converted to because it wasnt on the market, so the guys at Antaeus Labs decided to release it. Dienolone has very poor oral bio-availability so they put it into a topical delivery system (similar to the prescription testosterone preparation androgel) that they call Trenazone. It has an anabolic/androgenic ratio of 100/10 compared to methyltestosterone. This means it wont pose a very serious risk for hair loss or prostate issues in comparison to some of the other products on the market. This compound may pose more of a risk for those prone to gyno because it has a progesterone receptor affinity similar to that of nandrolone (deca), and because of its low androgenicity (high androgenic substances like DHT are our bodies natural defenses to estrogen and subsequently gyno).
Chemical Name
estra-4,9-dien-17b-ol-3-one
Maintaining Health
Trenazone is a very potent anabolic, and due to it bypassing the oral route for delivery it is essentially non-toxic to the liver in comparison to methylated anabolics. Side effects aren’t as severe with this compound in comparison to others, but with pro-hormones/designer-steroids there’s always some risk of side effects, thus properly planning for common side effects will help reduce any occurrences. Luckily many herbal based supplements have been scientifically shown to produce desirable results when it comes to Blood Pressure, Liver Function and Lipid profiles. Over the years several companies have begun creating “all-in-one” products designed specifically for prohormone and designer steroid cycles. These products have been a staple in thousands of users cycles with excellent results including blood work to backup their effectiveness. Therefore ANYONE running a cycle of Trenazone should use one of the following products throughout the entire Cycle:
All three are, for the most part, identical products. The biggest difference is the form, cost, and whether you prefer to take pills or powder. A general rule of thumb is to pre-load either one (Life Support or Cycle Support) one week prior to beginning your cycle and all the way through until the end, so buy accordingly so that you have enough on hand. These products will assist your body with maintaining healthy blood pressure, liver function and lipid profile. If running Trenazone solo, you can reduce the Life/Cycle support dosage by 25% to conserve money.
Dosing
This compound is often stacked with methylated products due to it adding minimal liver strain. Generally with Trenazone 1-1.5ml a day (75-112.5mg) is the most popular dosage, however experienced users with past pro-hormone or designer steroid experience can experiment with dosages in upwards of 2ml (150mg) per day.
Since this compound is not as hard on your body cycles can be extended up to 8 weeks in length with 6 weeks being the most common. Most users will begin to notice the effects by the third week in the form of muscle hardness/increased strength. Novice users should always stay within the general dosing amounts and not exceed 6 weeks in cycle length, although more experienced users can safely run it for 8 weeks.
Transdermal preparations have a very long half life, so once daily application of Trenazone would be ideal. The best place to apply Trenazone is the neck, particularly the lower neck above the clavicle, upper back, outer thighs, chest, and abdomen.
Side Effects
Side effects with Trenazone aren’t as common when used stand alone, however it can elevate blood pressure and alter lipid levels the same as any anabolic. Due to it having an affinity for the progesterone receptor gyno will be a possibility, however stacking this with a higher androgenic substance like epistane or stanodrol will help mitigate this.
With any designer steroid or pro-hormone side effects can occur and in most cases they’re avoidable by following proper on-cycle support guidelines. The following is a listing of some other possible side effects with Trenazone:
Typical Results
Results will vary based upon the dosage, however at most dosages Trenazone will slightly assist with decreasing bodyfat, increase muscle hardness, increase muscular size, enhance recovery, and promote more intensive workouts.
Its very hard to quantify results because Trenazone is often used to stack on top of other substances, but it does produce visible results if diet, training, and dosing are spot on.
Stacking
Trenazone is a popular stacker, because it is non-methylated which allows users to combine it with popular methylated anabolics such as Epistane. Typically users would want to stack this compound with higher androgenic substances to provide a balanced anabolic/androgenic effect. Trenazone can be utilized during either a bulk or a cut. Below is a short list of several anabolics Trenazone is commonly stacked with:
Methylated Compounds (Epistane, Methyl-Stenbolone, D-Plex, etc)Non-Methylated Compounds (Stanodrole, 1-DHEA, 11-oxo, etc)Post Cycle Therapy
Post cycle therapy is, as always, one of the most important parts of any cycle. If one does not work towards bringing their body back to homeostasis gains will be lost (making the health risks pointless) and the chance for side effects increases significantly. Trenazone will be more suppressive than a typical testosterone derivative. Once you stop taking a designer steroid or pro-hormone your body goes through a change of hormones and puts stress on your endocrine system. With a properly planned PCT (Post Cycle Therapy) we assist our body with easing back into normal function. Failure to follow a properly planned PCT can result in undesirable side effects such as:
Gynecomastia (Bitch Tits)AnxietyDepressionMuscle Loss/Fat GainSexual Side EffectsPCT Guidelines
You should begin your PCT regiment immediately after your pro-hormone or designer steroid cycle, it should begin the day after your last dosage of any anabolics. PCT regiments are typically 4-6 weeks depending on the type of compound being used, user, and type of PCT. As noted in the previous section under “Maintaining Health”, you should continue to use Life Support or Cycle Support throughout your entire cycle, INCLUDING your PCT regiment. During PCT we effectively want to achieve the following:
Restore Natural Testosterone ProductionRegulate EstrogenControl/Lower CortisolOver The Counter: An OTC (Over The Counter) post cycle therapy regiment is simply that, a PCT that consists with strictly over the counter products that can be bought at major supplement outlets such as BodyBuilding.com, Nutraplanet.com or stores such as Vitaminshoppe and GNC. Since Trenazone is a relatively mild if used alone, an over the counter PCT is acceptable for dosages of 75mg/day or less. Users utilizing a dosage of 75+mg or stacking with other anabolics should consider going with a SERM. In general if you have access to a SERM such as Nolvadex/Clomid/Toremifine, regardless of the dosage, it will be the most effective PCT tool. Compounds to utilize during an Over The Counter PCT are as follows:
D-Aspartic Acid (DAA). This is a compound recently discovered that has been shown in human studies to increase testosterone by 40%. The cost is low and it works through increasing gonadotropin levels which are at their lowest following prohormone cycles.PES Erase. This is an effective estrogen inhibitor that also mitigates the cortisol spike that occurs post cycle. Its extremely affordable and should be an inclusion to all PCTs in addition to D-Aspartic-Acid.PES AnaBeta. This is a natural anabolic that also has secondary characteristics of elevating testosterone. During PCT the main aim is to keep gains and bring hormone levels back to homeostasis. Including something that helps you stay anabolic in PCT will ensure that no gains are lost.Assuming you were using the products above, here is how you would schedule your PCT:
Days 1-30
D-Aspartic-Acid – 3 grams dailyErase – 3 capsules dailyAnaBeta – 4 capsules dailySelective Estrogen Receptor Modulator (SERM)
SERMs work by occupying the receptor binding site of estrogen. Once this binding takes place estrogen can no longer exert its negative feedback on the HPTA (Hypothalamic Pituitary Testicular Axis), resulting in increased testosterone levels. SERMs do not lower estrogen levels and in many cases increase them, so the concurrent use of an aromatase inhibitor is always the best course of action.
The MOST effective PCT regiment is one that includes a SERM prescription/research drug. Some users prefer not to go this route however, as they are “experimental” drugs and can have their own side effects. As such with a compound such as Trenazone a research drug really isn’t needed except for users running dosages 75mg or less. To obtain a SERM you’ll need a prescription or google for “research chemicals” as they can be purchased legally if being used for research purposes. The three main SERMs are as follows:
Below is an example dosing outline for each of these research drugs. This outlining should be combined with the over the counter PCT for the best recovery. Only one SERM should be used during any given PCT unless you’re an advanced user coming off months of hormone use. Nolvadex is the most commonly used SERM, however Clomid has been shown in scientific literature to regulate hormones in ex-steroid users.
Example 1 (Nolvadex PCT) Week 1-2 Nolvadex 20mg | Week 2-4 Nolvadex 10mg
Example 2 (Clomid PCT) Week 1-4 Clomid 50mg
Example 3 (Toremifine PCT) Week 1 Toremifine 90mg | Week 2 Toremifine 60mg | Week 3-4 Toremifine 30mg
Example Cycle
Week 1-2: Pre-load Cycle Support or Life Support @ Bottle Recommended dosages.Week 3-10: Cycle/Life Support | Trenazone 75-150mg dailyWeek 11-12: Cycle/Life Support | DAA | Erase | AnaBeta | Clomid 50mgWeek 12-13: Cycle/Life Support | DAA | Erase | AnaBeta | Clomid 50mgDrug Testing
Users who are at risk for anabolic steroid testing may test positive while using Trenazone. Always know whether or not you are at risk for drug testing prior to using Pro-Hormones/Designer Steroids.
Interactions
Users who are on anti-depressant or anti-anxiety medication may experienced increased anxiety/depression while on cycle and during PCT. Users should avoid using stimulants on cycle as blood pressure may elevate too high and possibly cause nose bleeds or even in some rare cases fainting. In general, avoid starting any new medications while on cycle or just before, if you’re concerned about a possible interaction consult your doctor. Users should also eat a clean diet on cycle and limit their alcohol intake significantly (best option would be to discontinue usage).
Disclaimer
We are not doctors, therefore before starting any supplement or training regiment you should consult with your doctor. The information being provided is simply personal opinion.
HTC’s “Desire” lineup to be revamped come November 27th
Monday, January 13, 2014
LMG Guide & Review (Max-LMG).
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Prelude & Overview
LMG (often referred to as Max LMG or M-LMG) is a progestin based designer seteroid/pro-hormone, LMG has been cloned considerably over the years, however the correct nomenclature for an LMG based compound is (13-ethyl-3-methoxy-gona-2,5(10)-diene-17-one ). Max LMG is a ‘wet’ non-methylated compound and considered to be relatively mild, while LMG is a wet compound it doesn’t aromatize therefore fluid retention can be limited. Max-LMG should be reserved for bulking due to water retention and possible bloating, it’s seldom used solo and is often part of a bulking stack in conjunction with a more potent methylated compound.
Note: There has been independent research challenging the notation that LMG doesn’t aromatize, research has shown that it does impact estrogen.
Below is a list of some confirmed Max LMG clones, however availability of these compounds may vary.
Alri – Max LMGAnabolic Xtreme - Ergomax LMGCompetitive Edge Labs – M-LMGGenetic Edge Technologies – SuS 500XS Labs – Tren 13-ethylBlack China Labs – Super Tren-MGDouble Dragon – MX75NRG-X Labs – Tren 13-EthylMaintaining Health
Max LMG is an oral based pro-hormone that’s processed by the liver, LMG is NOT a methylated compound and thus is considered relatively liver safe. Despite being a relatively mild compound LMG falls into the moderate category in terms of side effects, mostly as it’s a progestin therefore prolactin sides can be a concern, avoid stacking with other progestins. ALL steroids and pro-hormones can negatively impact blood pressure, lipid values, estrogen, cholesterol levels and will put stress on the bodies endocrine system, there is also additional side effects (discussed shortly) that can also present themselves, however in most cases they’re typically minor and a slight inconvenience.
With proper planning and preventative supplementation we can assist our bodies with protecting our livers, lipid values, cholesterol levels and help control adverse blood pressure effects, this may seem like a daunting task finding supplements to tackle all of these concerns, however luckily several supplement companies have been making “all-in-one” cycle protection products that work to address many of these potential side effects and subsequently an “all-in-one” product will be the basis for our on cycle support. Therefore ANYONE running LMG, is required to supplement with one of the following products throughout the entire duration of the cycle.
Anabolic Innovations – Cycle Support (Powder)Anabolic Innovations – Life Support (Capsules)Competitive Edge Labs – Cycle Assist (Capsules)Either of the three are suitable choices, cost should be the deciding factor or whether you prefer capsules or powder. A general rule of thumb is to pre-load either of the products two weeks prior to beginning your cycle and continue to use throughout the entire cycle from start to finish, buy accordingly so you have enough on hand. These products will assist your body with maintaining healthy blood pressure, prostate health, liver function and lipid profile by utilizing popular herbs such as Hawthorn Berry (BP), NAC (liver), Milk Thistle (liver), Saw Palmetto (prostate) among others. Please follow the manufactures recommended dosage (as per bottle) as it’s the dosage known to work best.
One of the potential downside’s of LMG is the potential of progestin sides including induced gyno or flare ups of existing gyno cases, while rare, we need to take this into consideration. Therefore it’s recommend all users run P-5-P on cycle, follow the recommended dosage on the bottle, if you experience any flare ups, bump the dosage into the 150-250mg range.
For more information on combating other sides please read our article combating cycle sides.
Dosing
There are a lot of possible length / dosage combinations with LMG, with the most common dosage being 100MG daily, cycles are anywhere from 4 to 7 weeks in length with 6 weeks being the most common. Advanced users can experiment with dosages in upwards of 150MG, however, if stacking with another compound adjust the dosage accordingly. Like most other steroids/pro-hormone for the effects to be in full gear it may take several weeks and that is the case with LMG as well, expect results by the third week. Dosages should be split by 6-8 hours as the half life for this compound is between 6 and 8 hours.
Below is the recommend cycle layout for good results with manageable risk of side effects.
Cycle Layout (6 Weeks):
Week 1: 75mg / per day
Week 2-6: 100mg / per day
On lifting days it’s recommended to take a dosage roughly one hour before starting your gym session, in some cases taking a dosage before bed may have a negative impact on sleep, so take this into consideration. In addition, it’s generally a good idea to take each dosage with EFA’s (i.e fish oil) in order to enhance absorption, it’s also recommended to consume 16+ ounces of water at each dosage
Common Side Effects
The occurrence rate of side effects while using LMG would be considered moderate, middle of the road in terms of sides, however they’re completely user unique, some users may not experience any side effects, while other users will experience a combination of sides. It should be noted that the majority of these side effects are simply of inconvenience more so than a possible health affecting issue and for the most part can be resolved through simple supplementation, take sometime to read our article on combating side effects. Keep in mind these potential side effects are in addition to those mentioned above under “Maintaining Health”…
Bloating / Water Retention.Hair sheddingAggravation of existing Gyno.Puffy / Sensitive NipplesJoint DiscomfortBack Pumps (Dull pain in back after/during workouts)Decreased Libido/Improved Libido (common)Increased aggression, head aches, flushing and various other sides can happen as well.Typical Results
LMG is a bulking compound through and through, expect very wet gains with weight loss post cycle due to bloating. Most feedback suggests excellent size and strength gains, however LMG truly shines when stacked with a methylated slightly more potent designer steroid/pro-hormone. Gains are user dependent some users may experience more size gains while others more strength gains and some an equal distribution of both. Gains in the 7-8lbs range, however some gains may simply be bloat which will be lost post cycle.
Post Cycle Therapy
Possibly the most important item on the menu is post cycle therapy, when taking a foreign substance (LMG) that creates testosterone your body begins to shut down it’s normal production, when you stop taking a pro-hormone or steroid compound your body needs a way to jump start it’s own natural production again, while limiting endocrine system stress, this is why we need post cycle therapy. It’s not just as simple as that however, when coming off of a compound your body goes through a very stressful phase as your hormones are out of balance, failure to mitigate these imbalances can result in a unique set of side effects not related to the LMG compound. Below is just a *few* of the noted side effects of an improper post cycle therapy regiment, it should also be noted that the occurrence of side effects in the post cycle stage is more common than the “on-cycle” phase, however a properly planned post cycle therapy regiment can mitigate these risks.
Gynecomastia (or Man Boobs)Anxiety/Depression (Can range mild to severe)Body Aches/Pains (Can range mild to severe)Impotence and other sexual function side effects.Loss of gains made on cycle.As you can see, these are side affects we definitely want to avoid at all costs, so let’s start discussing a proper LMG (Post Cycle Therapy).
Post Cycle General: You should begin your PCT regiment immediately after your pro-hormone or designer steroid cycle, it should begin the day after your last dosage of LMG PCT regiments are typically 4-6 weeks depending on the type of compound being used, user and type of PCT. As noted in the previous section under “Maintaining Health”, you should continue to use Life Support, Cycle Assist or Cycle Support throughout your entire cycle, INCLUDING your PCT regiment.
Boost Natural Testosterone Production.Regulate Estrogen.Restore HPTA function.Reducing SHBG.Control Cortisol Effects.Over The Counter: An OTC (Over The Counter) is possible with LMG (especially if being used standalone), however we advocate using a SERM for all compounds.
Research Drugs: The MOST effective PCT regiment is one that includes a prescription/research drug, however some users prefer not to go this route, you may be asking why would someone go another route if this is the most proven and effective PCT method. There’s various reasons but one to point out is that these drugs aren’t technically available without a prescription, these are also very powerful drugs that can also have their own side effects, notice that I say they aren’t “technically” available that’s because they can be purchased online at research drug sites, I won’t provide you with any links, if you chose to go this route googling for these sites will won’t take you long.
1. Nolvadex (Tamoxifen Citrate). Comes in Liquid or Pill form.
Below is an example PCT when using a research drug (such as Nolvadex aka Tamoxifen Citrate, as we are in this case). (If stacking run at least 20/20/10/10)
Week 1 Nolvadex 20mg | Week 1-3 Nolvadex 10mg
Example Cycle
This is an example cycle from start to finish to give you an idea how it should look, assumes you’re using Nolvadex. From start to finish our properly designed cycle will take approximately 12 weeks total. Assuming your cycle is 6 weeks in length.
Week 1-2: Pre-load Cycle Support, Cycle Assist or Life Support @ Bottle Recommended dosages.Week 3: Cycle/Life Support | LMG 75mgWeek 4-8: Cycle/Life Support | LMG 100mgWeek 9: Cycle/Life Support | Nolvadex 20mgWeek 10-12: Cycle/Life Support | Nolvadex 10mgStacking
LMG can easily be stacked with other compounds quite successfully,because it’s non-methylated the choices are virtually endless, the most popular addition to a LMG cycle is typically P-Mag/Superdrol. It’s viable to stack this compound with a steroid that’s a better mass gainer while experiencing the recomping effects from LMG.
Methylated Compounds (Halodrol, H-Drol, P-mag, Superdrol, M-Drol, Epistane, Havoc, etc)Non-Methylated Compounds (BOLD, 11-OXO, 3-AD, Furazadrol, etc)Supplements
It’s recommended that users supplement with a quality Multi-Vitamin and Fish Oil throughout the ENTIRE cycle. You should stop taking any other supplements on Cycle as well such as Creatine, NO, Test Boosters and so on, these should be saved for PCT in order to preserve strength. It’s heavily recommended that during PCT, you add Creatine and a Cell Volumizer type of product. Supplementing with Protein is highly recommended on cycle.
Interactions
Users who are on anti-depressant or anti-anxiety medication may experienced increased anxiety/depression while on cycle and during PCT. It is HEAVILY advised not to drink alcoholic drinks while on Cycle & PCT, doing so will put significant strain on the liver and can result in a major health hazard. Users should avoid using stimulants on cycle as blood pressure may elevate too high and possibly cause fainting. In general, avoid starting any new medications while on cycle or just before, if you’re concerned about a possible interaction consult your doctor. Users should also eat a clean diet on cycle.
Drug Testing
Those being tested for elevated testosterone levels and or lowered estrogen levels will produce a positive test result while on LMG, it’s also important to note that if using a research/prescription drug for your PCT regiment, this will also cause a positive test result in many cases. In the meantime the easiest method for passing a drug test is to purchase synthetic urine online, they come in easy to use kits at many websites and are relatively affordable.
Disclaimer
We are not doctors, therefore before starting any supplement or training regiment you should consult with your doctor. The information being provided is simply personal opinion. Anyone under the age of 21 should not consider using any pro-hormone or designer steroid as it can have a negative impact on your life, for life.
Google updates Wallet app to add cards via photo
Sunday, January 12, 2014
Strike Force Heroes Extraction game released for iPhone
1-DHEA – Powerful According to Researchers
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Posted by Androgen on August 07, 2013
Designer Steroids
1-DHEA is a prohormone to 1-Testosterone (dihydroboldenone). It is commonly sold under the brand name of “1-Andro” (1-Androsterone). 1-Andro is a non 17-aa prohormone requiring two steps in its conversion to 1-Test. Reduction of the 17-ketone functional group by 17b-HSD produces 1-Androstenediol while oxidation of the 3-hydroxyl group by 3a-HSD produces 1-Androstenedione. Both of these metabolites may have some intrinsic anabolic/androgenic properties, but it is their further conversion to 1-Testosterone that produces the anabolic muscle building effects seen from 1-Andro.
1-Andro appears weak structurally. It requires two enzymatic conversions to become the target hormone 1-Testosterone. Throw in the fact that it is technically a “DHEA” molecule, and most would believe it to be weak prohormone. However, a new study performed by West Texas A&M University shows otherwise.
9 males with an average of 5 years experience in resistance training and an average bodyfat of 13% were given 330 mg of 1-Andro daily for 4 weeks while completing a structured resistance training program. Data was collected pre-cycle and post-cycle on: lean mass, strength, lipids, and cardiac metabolic function. Studies like these are the holy grail of prohormone studies. They are very rare. When a study like this is performed on a prohormone, it is wise to take notice. These studies give better answers to the overly common questions of what kind of gains one can expect, what dose is best, and the degree of toxicity that comes from the prohormone.
Results showed 1-Andro to be significantly more powerful than it would appear structurally. The 9 males gained an average lean mass of 10.4 lbs and an increase in strength of 92.2 lbs in total load on bench/squat/deadlift. These are significant gains from a prohormone. It is important to keep in mind that these results were seen from 330 mg of pure 1-Andro taken daily. The recommended dosages on the internet vary from 100-800 mg per day; obviously 800 mg being excessive in retrospect to this study. It was interesting to note that cardiac metabolic function was negatively affected as evident by the increase in creatinine and aspartate transaminase (AST). Lipids were also negatively effected; an increase in LDL and decrease in HDL were observed.
The researchers concluded that “The prohormone supplement contributed to robust improvements in muscle mass and strength in resistance trained males but these gains came at the price of subject’s cardio-metabolic function.” These negative side effects are most likely caused by 1-Andro’s conversion to the potent steroid 1-Testosterone and not caused by 1-Andro itself. Of course, the elevated enzymes and negatively impacted lipids were expected to return to baseline some weeks after the cycle. Although repeated studies are necessary to substantiate the efficacy of any compound, it’s safe to say that 1-Andro definitely packs a punch!
Grandos J, Gillum T, Hodges C, Kuennen M. 3-hydroxy-5alpha-androst-1-en-17-one Enhances Muscular Gains but Impairs the Cardio-metabolic Health of Resistance Trained Males. International Journal of Exercise Science.Tags: 1-Andro, 1-Androsterone, 1-DHEA, increase strength, muscle building, toxicityLG G Flex drop test, curved doesn’t mean unbreakable
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1-Androsterone (1-Testosterone) – Guide
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1-androsterone (aka 1-DHEA) is a prohormone that undergoes a two step conversion through the enzymes 3b-hsd and 17b-hsd to become the potent androgen 1-Testosterone. 1-Testosterone is a DHT derivative, therefore this compound or its converted forms can not convert to estrogens. Once in its final form this compound has about twice the anabolic potency of testosterone with similar androgenicity (200/100 vs 100/100 in vida).
1-DHEA is one of the milder compounds available on a mg per mg basis, and its also not methylated so it isn’t inherently toxic to the liver (although its been noted that non-methylated compounds still produce elevated liver enzymes if abused). Side effects aren’t as severe with this compound in comparison to others, but with pro-hormones/designer-steroids there’s always some risk of side effects, thus properly planning for common side effects will help reduce any occurrences. Luckily many herbal based supplements have been scientifically shown to produce desirable results when it comes to Blood Pressure, Liver Function and Lipid profiles. Over the years several companies have begun creating “all-in-one” products designed specifically for prohormone and designer steroid cycles. These products have been a staple in thousands of users cycles with excellent results including blood work to backup their effectiveness. Therefore ANYONE running a cycle of 1-DHEA/1-Androsterone should use one of the following products throughout the entire Cycle:
Anabolic Innovations – Life Support (Capsules)Anabolic Innovations – Cycle Support (Powder)Competitive Edge Labs – Cycle Assist (Capsules)All three are, for the most part, identical products. The biggest difference is the form, cost, and whether you prefer to take pills or powder. A general rule of thumb is to pre-load either one (Life Support or Cycle Support) one week prior to beginning your cycle and all the way through until the end, so buy accordingly so that you have enough on hand. These products will assist your body with maintaining healthy blood pressure, liver function and lipid profile. If running 1-DHEA/1-Androsterone solo, you can reduce the Life/Cycle support dosage by 25% to conserve money.
Dosing
The dosing one chooses to work with varies greatly on whether they are stacking this compound with other anabolics or running it solo. Generally with 1-DHEA 300-600mg a day is the most popular dosage, however experienced users with past pro-hormone or designer steroid experience can experiment with dosages in upwards of 700-1000mg. The added benefit may be negligible at this dosage and the likely-hood of side effects sharply increases..
Since this compound is not as hard on your body cycles can be extended up to 8 weeks in length with 6 weeks being the most common. Most users will begin to notice the effects by the third week in the form of muscle hardness/increased strength. Novice users should always stay within the general dosing amounts and not exceed 6 weeks in cycle length, although more experienced users can safely run 1-DHEA for 8 weeks.
You should split up your dosages into 2-3 different times throughout the day, ideally separated by 5-6 hours (or 8 hours if two daily dosages). For the ideal results, take your largest dosage 45 minutes to one hour before your workout session.
Side Effects
Side effects with 1-DHEA aren’t common when used stand alone, however many users experience marked lethargy from this compound. Due to it having significant androgenic potency and the inability to convert to estrogen, water retention and gynecomastia are rarely reported. The level of androgenicity this compound has may also pose as a hair loss risk for users prone to male pattern baldness, however reports of this are not many. With any designer steroid or pro-hormone side effects can occur and in most cases they’re avoidable by following proper on-cycle support guidelines. The following are a listing of some other possible side effects with 1-Andro/1-DHEA:
Decreased Libido/Sexual FunctionAnxiety / Stimulated FeelingAggressionSlightly increased Blood PressureBack Pumps (Dull pain in back after/during workouts)Typical Results
Results will vary based upon the dosage, however at most dosages 1-DHEA will slightly assist with decreasing bodyfat, increase muscle hardness, enhance recovery and promote more intensive workouts.
Gains in the realm of 5-9lbs with a loss of 1-2% bodyfat are not unheard of with a 6 week cycle @ 600mg/day of this compound. Its very hard to quantify results because 1-DHEA is often used to stack on top of other substances, but it does produce lean visible results if diet, training, and dosing are spot on.
Stacking
1-DHEA is a popular stacker, this is because it’s relatively mild and non-methylated which allows users to stack this substance with popular methylated anabolics such as Halodrol. Typically users would want to stack this compound with lower androgenicl substances to provide a balanced anabolic/androgenic effect. 1-DHEA can be utilized during either a bulk or a cut. Below is a short list of several anabolics 1-DHEA is commonly stacked with:
Methylated Compounds (H-Drol, P-mag, Superdrol, etc)Non-Methylated Compounds (11-OXO, 4-DHEA, Furazadrol, M-LMG, etc)Post Cycle Therapy
Post cycle therapy is, as always, one of the most important parts of any cycle. If one does not work towards bringing their body back to homeostasis gains will be lost (making the health risks pointless) and the chance for side effects increases significantly. Once you stop taking a designer steroid or pro-hormone your body goes through a change of hormones and puts stress on your endocrine system. With a properly planned PCT (Post Cycle Therapy) we assist our body with easing back into normal function. Failure to follow a properly planned PCT can result in undesirable side effects such as:
Gynecomastia (Bitch Tits)AnxietyDepressionMuscle Loss/Fat GainSexual Side EffectsPCT Guidelines
You should begin your PCT regiment immediately after your pro-hormone or designer steroid cycle, it should begin the day after your last dosage of any anabolics. PCT regiments are typically 4-6 weeks depending on the type of compound being used, user, and type of PCT. As noted in the previous section under “Maintaining Health”, you should continue to use Life Support or Cycle Support throughout your entire cycle, INCLUDING your PCT regiment. During PCT we effectively want to achieve the following:
Restore Natural Testosterone ProductionRegulate EstrogenControl/Lower CortisolOver The Counter: An OTC (Over The Counter) post cycle therapy regiment is simply that, a PCT that consists with strictly over the counter products that can be bought at major supplement outlets such as BodyBuilding.com, Nutraplanet.com or stores such as Vitaminshoppe or GNC. Since 1-DHEA is a relatively mild compound, an over the counter PCT is acceptable for dosages in the 300-600mg range. Users utilizing a dosage of 600+mg or stacking with other anabolics should consider going with a SERM. In general if you have access to a SERM such as Nolvadex/Clomid/Toremifine, regardless of the dosage, it will be the most effective PCT tool. Compounds to utilize during an Over The Counter PCT are as follows:
D-Aspartic Acid (DAA). This is a compound recently discovered that has been shown in human studies to increase testosterone by 40%. The cost is low and it works through increasing gonadotropin levels which are at their lowest following prohormone cycles.PES Erase. This is an effective estrogen inhibitor that also mitigates the cortisol spike that occurs post cycle. Its extremely affordable and should be an inclusion to all PCTs in addition to D-Aspartic-Acid.PES AnaBeta. This is a natural anabolic that also has secondary characteristics of elevating testosterone. During PCT the main aim is to keep gains and bring hormone levels back to homeostasis. Including something that helps you stay anabolic in PCT will ensure that no gains are lost.Assuming you were using the products above, here is how you would schedule your PCT:
Days 1-30
D-Aspartic-Acid – 3 grams dailyErase – 3 capsules dailyAnaBeta – 4 capsules dailySelective Estrogen Receptor Modulator (SERM)
SERMs work by occupying the receptor binding site of estrogen. Once this binding takes place estrogen can no longer exert its negative feedback on the HPTA (Hypothalamic Pituitary Testicular Axis), resulting in increased testosterone levels. SERMs do not lower estrogen levels and in many cases increase them, so the concurrent use of an aromatase inhibitor is always the best course of action.
The MOST effective PCT regiment is one that includes a SERM prescription/research drug. Some users prefer not to go this route however, as they are “experimental” drugs and can have their own side effects. As such with a compound such as 1-DHEA a research drug really isn’t needed except for users running dosages above 600mg. To obtain a SERM you’ll need a prescription or google for “research chemicals” as they can be purchased legally if being used for research purposes. The three main SERMs are as follows:
Nolvadex (Tamoxifen Citrate). Comes in Liquid or Pill form.Clomid (Clomiphene Citrate). Comes in Liquid or Pill form.Fareston (Toremifine Citrate). Comes in Liquid or Pill form.Below is an example dosing outline for each of these research drugs. This outlining should be combined with the over the counter PCT for the best recovery. Only one SERM should be used during any given PCT unless you’re an advanced user coming off months of hormone use. Nolvadex is the most commonly used SERM, however Clomid has been shown in scientific literature to regulate hormones in ex-steroid users.
Example 1 (Nolvadex PCT) Week 1-2 Nolvadex 20mg | Week 2-4 Nolvadex 10mgExample 2 (Clomid PCT) Week 1-4 Clomid 50mgExample 3 (Toremifine PCT) Week 1 Toremifine 90mg | Week 2 Toremifine 60mg | Week 3-4 Toremifine 30mgExample Cycle
Week 1-2: Pre-load Cycle Support or Life Support @ Bottle Recommended dosages.Week 3-10: Cycle/Life Support | 1-DHEA 300-600mg dailyWeek 11-12: Cycle/Life Support | DAA | Erase | AnaBeta | Nolvadex 20mgWeek 12-13: Cycle/Life Support | DAA | Erase | AnaBeta | Nolvadex 10mgDrug Testing
Users who are at risk for anabolic steroid testing will test positive while using 1-DHEA due to the metabolites of 1-Testosterone that are excreted during use. Always know whether or not you are at risk for drug testing prior to using Pro-Hormones/Designer Steroids.
Common Clones
Here is a short list of products that use 1-DHEA:
IronMagLabs – 1-Andro RXPrimordial Performance – AndroMassPrimordial Performance – 1T (discontinued)AMS – 1-AndrosteroneForerunner Labs – AlphaMassIts worth noting that while some products may not meet the recommended dosing as outlined in this article, they utilize special delivery mechanisms to enhance absorption/conversion to the target metabolites 1-androdiol(dione) and 1-testosterone.
Interactions
Users who are on anti-depressant or anti-anxiety medication may experienced increased anxiety/depression while on cycle and during PCT. Users should avoid using stimulants on cycle as blood pressure may elevate too high and possibly cause nose bleeds or even in some rare cases fainting. In general, avoid starting any new medications while on cycle or just before, if you’re concerned about a possible interaction consult your doctor. Users should also eat a clean diet on cycle and limit their alcohol intake significantly (best option would be to discontinue usage).
Disclaimer
We are not doctors, therefore before starting any supplement or training regiment you should consult with your doctor. The information being provided is simply personal opinion.
Saturday, January 11, 2014
OTC Anti-Estrogens
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Anti-estrogens have many purposes for the chemically enhanced athlete. Many of the drier “contest prep” androgens that bodybuilders use gain much of their affect due to antagonizing estrogen at both the receptor site and inhibiting its creation all together. For those that wish to not use anabolics then anti-estrogens are much desired because they can help you achieve a better hormonal alignment without actually having to ingest hormones. Anti-estrogens can:
Prevent (or reverse) gynoReduce estrogen related bloatEnsure a cycle with aromatizing androgens is drier/leanerIncrease testosterone levels – very beneficial during PCTAid in fat loss (estrogen is a lipogenic hormone)Aromatase is the enzyme that converts male hormones to female estrogens. It is the primary way men create estrogen and failure to control this on cycles of aromatizing androgens like M14AD may produce very unsightly side effects. The most commonly used OTC anti-estrogens work through inhibiting this enzyme, and they will be covered below.
ATD is a supplement that gained huge exposure in numerous OTC PCT products over the past several years. It is a suicidal inhibitor of the aromatase enzyme, meaning that once the drug has been discontinued enzyme levels slowly return to baseline. Suicidal inhibitors are often preferred because there is no “rebound” in estrogens after coming off.
Scientific data on ATD shows it to be an effective anti estrogen and also would lead you to believe it produces immense increases in testosterone, however other data shows it produces a steroidal metabolite known as 1,4,6 Testosterone. The production of this weak androgen (about ? the potency of testosterone) causes false readings on testosterone serum tests.ATD has huge amounts of anecdotal feedback claiming it markedly reduces sex drive, but it was largely speculated that this was due to a substantial decrease in estrogen (low or high estrogen in males will reduce libido). Scientific literature has pointed us in another direction and shown that ATD is actually anti-androgenic (the complete opposite of what we would want).
The claims that this is great in PCT are nil when the data has been observed. It will reduce estrogen, but also occupy the androgen receptor and not allow testosterone to bind. The 1,4,6 testosterone metabolite would also theoretically produce HPTA suppression if the dose is significant.
ATD Pros:
Common Products:
Formestane is another suicidal inhibitor of the aromatase enzyme. It was originally studied as a pharmaceutical injection treatment for breast cancer but was pulled off the market in favor of other anti-estrogenic drugs. Formestane has been shown to reduce estrogen content within the body by 50%, so while not being as potent as some pharmaceuticals it does provide a nice reduction in levels.
Formestane will convert to the substance 4-hydroxytestosterone within the body, and this may make it hinder recovery if used during PCT. Formestane and 4-hydroxytestosterone can inhibit the enzyme 5-alpha reductase, which is responsible for creating DHT. This also makes formestane a less desired approach to combat gyno because DHT is our bodies natural defense against estrogen. Studies even show that DHT therapy alone can reverse gyno in men, so it isnt exactly something suitable if reducing it might cost you a pair of moobs. Reduction of 5-alpha reductase is favorable for those prone to male pattern baldness, so those ingesting aromatizing androgens may have a safer bet using formestane to mildly reduce androgenic hormones and also estrogen if hair loss, but not gyno, is a concern.
Formestane has very poor oral bioavailability so a transdermal preparation is often the preferred mode for ingesting this substance. If oral products are to be used doses should be 150+mg per day.
Formestane Pros:
Common Products
CEL Formestane (Topical)Primordial Performance Formestane (Oral)
Androsta-3,5-diene-7,17-dione
(Erase)
This is the newest anti-estrogenic compound on the market. It is a suicidal inhibitor like the others above but has a few distinct alterations. First, this compound is unable to convert to a steroidal metabolite. This means that it is very favorable during PCT because HPTA suppression is impossible. The 7-oxo that this compound has also makes it good at reducing the catabolic hormone cortisol, which spikes after coming off your cycle.
Studies on the affinity for the aromatase enzyme show that this compound is actually more potent than the pharmaceutical compound Aromasin. The difference in bioavailability between the two is in favor of Aromasin, so that means that this compound would need to be ingested at slightly greater dosages (50-75mg vs 25mg).
Androst-3,5-dien-7,17-dione Pros:
Aromatizing Prohormones
Anti Estrogens should be considered on any of the following compounds to reduce the likelihood of side effects:
Methyl 1,4-AD (M14AD)Ment DioneM-LMGBoladrolAnti-estrogens may not be needed on cycles containing prohormones that do not convert to estrogen, but there has been reports of hormones causing gyno regardless of estrogen conversion. This likely happens from the bodies response to increased androgen levels, which then causes adrenal hormones to convert more readily into estrogens. This can also be combated by using one of the above anti-estrogens, and should typically be your first resort if pharmaceutical preparations are not within reach.
Disclaimer
We are not doctors, therefore before starting any supplement or training regiment you should consult with your doctor. The information being provided is simply personal opinion.
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Slimmer Summer Cycle – HDROL & 11-OXO
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Introduction
Summer is just around the corner, with summer fast approaching the time to cycle is limited, so we bring to you our slimmer summer Cycle featuring two well known pro-hormones/designer steroids, Halodrol and 11-OXO. Both are excellent candidates for a cutting cycle in their own right, but together the results are kicked into high gear.
H-Drol (Halodrol)
Halodrol (H-Drol) is a methylated designer steroid created by Gaspari Nutrition, the chemical makeup is (4-Chloro-17a-Methyl-Androst-1,4-Diene-3-17b-Diol), h-drol is methylated therefore it puts stress on our livers, h-drol shouldn’t be stacked with another methylated compound and should be ran with appropriate liver support. H-drol is quite potent and works well while cutting, recomping or bulking and is mild enough to be stacked with other non-methylated compounds (such as 11-OXO).
11-OXO (Andrenosterone)
11-OXO (Andrenosterone) is a non methylated designer steroid created by Ergopharm and has been widely cloned (11-test, 11-sterone etc). 11-OXO not only will assist with weight loss but it also positively impacts cortisol which has brings additional weight loss benefits, these effects in my cycle were quite noticeable within the first two weeks. This is a mild compound that stacks nicely with just about any compound on the market.
Orastan-A/Furazadrol
Since 11-OXO can be hard to find and expensive, Orastan-A/Furazadrol (and clones) can be used as a direct replacement for 11-OXO. The only tangible difference would be the dosage, if you’re opting to use an Orastan-A clone follow this dosing.
Dosing: 150mg to 250mg per day.
Bodily Protection
Like many compounds on the market 11-OXO and h-drol can have a negative impact on blood pressure, lipid values, cholesterol levels and will stress our bodies endocrine system, in the case of h-drol as noted it will also put additional strain on our livers. Anytime you’re stacking two designer anabolic steroids or pro-hormones the potential for side effects is elevated, however with proper supplementation and planning we can help our bodies mitigate most of the risk and or reduce the severity of side effects. Luckily for the past couple of years companies have been offering all-in-one cycle protection that are designed specifically to help prevent side effects and or in the event of side effects (such as elevated blood pressure) reduce their impact. Therefore ANYONE running a stack like this is required to supplement with one of the following products throughout the entire duration of the cycle.
Anabolic Innovations – Cycle Support (Powder)Anabolic Innovations – Life Support (Capsules)Competitive Edge Labs – Cycle Assist (Capsules)Either of the three are suitable choices, cost should be the deciding factor or whether you prefer capsules or powder. For this stacked cycle begin pre-loading either life support or cycle support one week before starting the cycle, make sure you run one of these products through the entire duration of your cycle including PCT so make sure you buy enough. These products will assist your body with maintaining healthy blood pressure, prostate health, liver function and lipid profile by utilizing popular herbs such as Hawthorn Berry (BP), NAC (liver), Milk Thistle (liver), Saw Palmetto (prostate) among others. Please follow the manufactures recommended dosage (as per bottle) as it’s the dosage known to work best.
Dosing & Length
We won’t get into all the dosing possibilities, because they’re so many options, but for this theoretical stack below is the dosing and length we will be using. We keep the dosage low on 11-OXO mostly to gain it’s cortisol benefits, feel free to bring the dosage up higher if you feel comfortable.
CompoundWeek 1Week 2Week 3Week 4Week 5Week 6Week 7Week 8Post Cycle Therapy (PCT)
As noted this article assumes you have past anabolic steroid or pro-hormone experience therefore we won’t get into WHY you need to PCT, please read our informative bibles on h-drol and 11-OXO for that information. For this stack you will most definitely need a prescription grade PCT utilizing a SERM and Nolvadex (Tamoxifen Citrate) fits that bill and is also the most popular SERM among steroid and pro-hormone users below is how this stacks PCT is being laid out.
Nolvadex (Tamoxifen Citrate). Comes in Liquid or Pill form.Optional (But highly-recommended): Competitive Edge Labs – P.C.T AssistBelow is the example PCT when using a research drug (such as Nolvadex aka Tamoxifen Citrate, as we are in this case).
Week1-2 Nolvadex 20mg & P.C.T Assist (5 caps) | Week 3-4 Nolvadex 10mg & P.C.T Assist (5 caps) | Week 5 P.C.T Assist (4 caps)
Putting it together
Here is how the cycle would look on paper from start to finish, including everything.
Wk1Wk2Wk3Wk4Wk 5Wk6Wk7Wk8Wk9Wk10Wk11Wk12Wk13Closing Arguments
This cycle should yield excellent cutting results, remember in the end it all comes down to diet and training.
Supplements
It’s recommended that users supplement with a quality Multi-Vitamin and Fish Oil throughout the ENTIRE cycle, keep something on hand for your joints in the event you experience some discomfort Universal Animal Flex works wonders. You should stop taking any other supplements on Cycle as well such as Creatine, NO, Test Boosters and so on, these should be saved for PCT in order to preserve strength. It’s heavily recommended that during PCT, you add Creatine and a Cell Volumizer type of product. Supplementing with Protein is highly recommended on cycle
Interactions
Users who are on anti-depressant or anti-anxiety medication may experienced increased anxiety/depression while on cycle and during PCT. It is HEAVILY advised not to drink alcoholic drinks while on Cycle & PCT, doing so will put significant strain on the liver and can result in a major health hazard. Users should avoid using stimulants on cycle as blood pressure may elevate too high and possibly cause fainting. In general, avoid starting any new medications while on cycle or just before, if you’re concerned about a possible interaction consult your doctor. Users should also eat a clean diet on cycle.
Disclaimer
We are not doctors, therefore before starting any supplement or training regiment you should consult with your doctor. The information being provided is simply personal opinion.
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Friday, January 10, 2014
Androxal – The Future of Testosterone Replacement Therapy
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Secondary hypogonadism is an unfortunate reality for many men. It is a natural condition that comes with age. The two parts of the brain; the hypothalamus and the pituitary gland which regulate testosterone production become less functional as a result of disease, inflammation, obesity, medications, but mostly as a result of aging. As many as 40% of men aged 45 or older will experience hypogonadism (1). Steroid users are at an even greater risk of attaining hypogonadism earlier in life. Being deficient in testosterone is not a pleasant experience by any means. Hypogonadal men may experience loss of muscle mass, low energy levels and libido, weak bone density, and be more prone to gaining fat mass. In recent times the benefits of Testosterone Replacement Therapy (TRT) have become alluring for many men; improvement in energy levels, libido, concentration, bone density, and an increase in muscle mass and decrease in fat mass.
While TRT may improve the symptoms of low testosterone, it does not come without a price tag. Current TRT programs administer testosterone via weekly injections or by transdermal applications. Both routes have their drawbacks. The idea of performing weekly injections for years on end is not appealing for anyone and transdermal applications can be easily passed by contact. Furthermore, the administration of exogenous testosterone causes the testicles to shrink and become non-functional further damaging the HPTA axis. This leads to infertility and a poor metabolic state negatively affecting Thyroid-stimulating hormone (TSH), Adrenocorticotropic hormone (ACTH), cortisol, and lipids.
In comes Androxal: an oral drug which causes the pituitary to release LH and FSH and in turn stimulates the testicles to produce testosterone. Thus the user actually experiences an increase in fertility, testicular function, and does not have to worry about being in a poor metabolic state. Androxal has been shown to posses all the positive benefits of AndroGel without the negatives side effects. In a study involving 44 men Androxal (25mg) increased serum testosterone levels to an average of 604 ng/dL while AndroGel increased serum testosterone levels to an average of 500 ng/dL after six weeks of continuous use (2). There is no potential for abuse with Androxal and it is not a controlled substance. Androxal is currently in phase 3 trials which are the final trials for confirming safety and efficacy before launch. Earlier this month, Bank of America initiated a buy on Repros Therapeutics, the makers of Androxal knowing full well it has potential to be the best method of TRT on the market.
So, what exactly is Androxal? It is an orally active single isomer of clomiphene citrate (clomid). Androxal constitutes the trans-stereoisomer of clomiphene citrate known as enclomiphene. It took long enough for the medical community to notice…
1. Mulligan T, Frick MF, Zuraw QC, et al. Prevalence of hypogonadism in males aged at least 45 years: The HIM study. Int J Clin Pract 2006;60:762-769.
2. Wiehle R. et al. Testosterone Restoration by Enclomiphene Citrate in Men with Secondary Hypogonadism: Pharmacodynamics and Pharmacokinetics. DOI: 10.1111/bju.12363
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The Methylstenbolone/Ultradrol – Guide
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MethylStenbolone is a very new and potent designer steroid recently brought to the market by Antaeus labs. Several products in the past have claimed to use this compound, however independent lab testing has revealed they only contained superdrol.
Methylstenbolone does not convert to an estrogenic metabolite or have any affinity for the progesterone receptor, so estrogen mediated side effects should be virtually non-existent. Methylstenbolone is also one of the most toxic substances available due to its ability to resist metabolization, although anecdotal reports lead us to believe it carries less side effects than superdrol.
Chemical Name
2,17a-dimethyl-5a-androsta-1-en-17ß-ol-3-one
Available Products
Maintaining Health
Methylstenbolone, like all methylated DS/PHs, is toxic to the liver. Methylsten is more potent than many other PHs (epi, hdrol, m14ad, etc) because it is a di-methyl androgen resistant of typical metabolic deactivating pathways, like 3b-hsd and 17b-hsd. Being one of the harshest compounds on the market it will negatively impact blood pressure, lipid values, cholesterol levels and will put stress on the bodies endocrine system.
With proper planning and preventative supplementation we can assist our bodies with protecting our livers, lipid values, cholesterol levels and help control adverse blood pressure effects. This may seem like a daunting task finding supplements to tackle all of these concerns, however several supplement companies have been making “all-in-one” cycle protection products that work to address many of these potential side effects. ANYONE running Methylsten is required to supplement with one of the following products throughout the entire duration of the cycle:
Advanced Muscle Science – Super Cycle (Capsules)Anabolic Innovations – Cycle Support (Powder)Anabolic Innovations – Life Support (Capsules)All three are, for the most part, identical products. The biggest difference is the form, cost, and whether you prefer to take pills or powder. A general rule of thumb is to pre-load either one 1-2 weeks prior to beginning your cycle and all the way through until the end, so buy accordingly so that you have enough on hand. These products will assist your body with maintaining healthy blood pressure, lipid profile, and provide mild protection to the liver.
Additional Liver Protection
While many cycle support products contain ingredients that are great anti-oxidants in liver tissue, they do not appear to impact bile acid secretion/metabolism at their given doses. The ingredients TUDCA and UDCA should be utilized on any oral steroid cycle (especially Methylstenbolone and Superdrol) as they have profound abilities at preventing and even reversing anabolic steroid induced liver damage, something milk thistle wont do. The following products utilize the ingredient TUDCA and should be considered for any oral androgen cycle:
Antaeus Labs – AegisThermolife – Liver LongerDosing
Methylsten is a very strong compound therefore it’s best to start with a lower dosage to asses tolerance and slowly increase it into the desired range. Methylsten cycles are typically 3-4 weeks in length with 4 weeks being the most common. Due to the extreme potency and toxicity of this compound use for longer than 4 weeks is not recommended. Below are two common dosing protocols:
Methylsten dosing for new users: Week1: 4-8mg / per day | Week 2-3: 8mg / per dayMethylsten dosing for experienced users: Week1: 8mg / per day | Week 2-3: 12mg / per day | Week 4: 16mg / per dayMethylsten works relatively quickly, therefore the majority of users typically begin to experience the effects within the first week. .
Common Side Effects
Side effects from methylsten would, in theory, be very similar to those from Superdrol, however almost all of the anecdotal feedback circulating suggests it is much kinder in this regard. It should be noted that the majority of these side effects are simply of inconvenience more so than a possible health affecting issue and for the most part can be resolved through proper on cycle support usage and proper PCT. These side effects are as follows:
Decreased Libido/Sexual FunctionLethargy / FatigueIncreased hair growth / Increased hair sheddingPuffy / Sensitive NipplesJoint DiscomfortBack Pumps (Dull pain in back after/during workouts)Increased aggression, head aches, flushing and various other sides can happen as well.Typical Results
Results will vary based upon the dosage, experience, diet and many other factors involved. In general Methylsten will provide exceptional lean body mass gains, excellent strength gains, and great endurance in the gym. This substance works best when used in a bulk due to it’s ability to help our bodies pack on the muscle when eating a clean caloric surplus diet, but that doesn’t mean it cant also be used in a cutting or recomp cycle. There are just more favorable compounds to utilize during those types of cycles.
When used in a bulking diet, gains can range from 15-20bs on a 4 week cycle at 12mg.When used in a recomp diet, gains can range from 7-10lbs on a 4 week cycle at 12mg, while also possibly reducing body fat 0-2%.When used in a cutting diet, gains can range from 4-6lbs on a 4 week cycle at 12mg, while also possibly reducing body fat 1-3%.The ‘gain’ ranges above are considered normal, however some users have reported gains in upwards of 20lbs and some users may not experience very noticeable gains at all. Results are largely dictated by diet.
Post Cycle Therapy
Post cycle therapy is, as always, one of the most important parts of any cycle. If one does not work towards bringing their body back to homeostasis gains will be lost (making the health risks pointless) and the chance for side effects increases significantly. Once you stop taking a designer steroid or pro-hormone your body goes through a change of hormones and puts stress on your endocrine system. With a properly planned PCT (Post Cycle Therapy) we assist our body with easing back into normal function. Failure to follow a properly planned PCT can result in undesirable side effects such as:
Gynecomastia (Bitch Tits)AnxietyDepressionMuscle Loss/Fat GainSexual Side EffectsPCT Guidelines
You should begin your PCT regiment immediately after your pro-hormone or designer steroid cycle, it should begin the day after your last dosage of any anabolics. PCT regiments are typically 4-6 weeks depending on the type of compound being used, user, and type of PCT. As noted in the previous section under “Maintaining Health”, you should continue to use Life Support or Cycle Support throughout your entire cycle, INCLUDING your PCT regiment. During PCT we effectively want to achieve the following:
Restore Natural Testosterone ProductionRegulate EstrogenControl/Lower CortisolOver The Counter: An OTC (Over The Counter) post cycle therapy regiment is not acceptable PCT for methylsten cycles. A research drug/SERM is REQUIRED before using this substance.
Selective Estrogen Receptor Modulator (SERM)
SERMs work by occupying the receptor binding site of estrogen. Once this binding takes place estrogen can no longer exert its negative feedback on the HPTA (Hypothalamic Pituitary Testicular Axis), resulting in increased testosterone levels. SERMs do not lower estrogen levels and in many cases increase them, so the concurrent use of an aromatase inhibitor is always the best course of action.
PCT Supports
While not a replacement for a SERM, many compounds being introduced on the market will help ensure recovery and maintenance of gains once entering the PCT phase and should be considered.
D-Aspartic Acid (DAA). This is a compound recently discovered that has been shown in human studies to increase testosterone by 40%. The cost is low and it works through increasing gonadotropin levels which are at their lowest following prohormone cycles.PES Erase. This is an effective estrogen inhibitor that also mitigates the cortisol spike that occurs post cycle. Its extremely affordable and should be an inclusion to all PCTs in addition to D-Aspartic-Acid.PES AnaBeta. This is a natural anabolic that also has secondary characteristics of elevating testosterone. During PCT the main aim is to keep gains and bring hormone levels back to homeostasis. Including something that helps you stay anabolic in PCT will ensure that no gains are lost.The MOST effective PCTregiment is one that includes a SERM prescription/research drug. Some users prefer not to go this route as they are “experimental” drugs and can have their own side effects, however with compounds as strong as methylsten they are required to restore hormones to homeostasis. To obtain a SERM you’ll need a prescription or google for “research chemicals” as they can be purchased legally if being used for research purposes. The three main SERMs are as follows:
Nolvadex (Tamoxifen Citrate). Comes in Liquid or Pill form.Clomid (Clomiphene Citrate). Comes in Liquid or Pill form.Fareston (Toremifine Citrate). Comes in Liquid or Pill form.Below is an example dosing outline for each of these research drugs. This outlining should be combined with the PCT supports for the best recovery. Only one SERM should be used during any given PCT unless you’re an advanced user coming off months of hormone use. Nolvadex is the most commonly used SERM, however Clomid has been shown in scientific literature to regulate hormones in ex-steroid users.
Example 1 (Nolvadex PCT) Week 1-2 Nolvadex 20mg | Week 2-4 Nolvadex 10mgExample 2 (Clomid PCT) Week 1-4 Clomid 50mgExample 3 (Toremifine PCT) Week 1 Toremifine 90mg | Week 2 Toremifine 60mg | Week 3-4 Toremifine 30mgExample Cycle
Week 1-2: Pre-load Cycle Support & Liver Longer @ Bottle Recommended dosages.Week 3: Cycle/Life Support/Liver Longer | Methylsten 8mg/dayWeek 4-6: Cycle/Life Support/Liver Longer | Methylsten 12mg/dayWeek 7-8: Cycle/Life Support | DAA | Erase | AnaBeta | Nolvadex 20mgWeek 9-10: Cycle/Life Support | DAA | Erase | AnaBeta | Nolvadex 10mgDrug Testing
Users who are at risk for anabolic steroid testing will test positive while using Methylstenbolone. Always know whether or not you are at risk for drug testing prior to using Pro-Hormones/Designer Steroids.
Interactions
Users who are on anti-depressant or anti-anxiety medication may experienced increased anxiety/depression while on cycle and during PCT. Users should avoid using stimulants on cycle as blood pressure may elevate too high and possibly cause nose bleeds or even in some rare cases fainting. In general, avoid starting any new medications while on cycle or just before, if you’re concerned about a possible interaction consult your doctor. Users should also eat a clean diet on cycle and limit their alcohol intake significantly (best option would be to discontinue usage).
Disclaimer
We are not doctors, therefore before starting any supplement or training regiment you should consult with your doctor. The information being provided is simply personal opinion.
Thursday, January 9, 2014
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Triumph for Trestolone: Myelin Regeneration
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Posted by Androgen on August 08, 2013
Designer Steroids
Myelin is a waxy protein substance coating the axon body of a neuron. It allows for proper electrical and chemical signaling down the axon of a neuron. This myelin coating is known as the myelin sheath and is necessary for proper functioning of our brain and nervous system. Demyelination is the loss of this myelin coating and leads to a wide array of negative side effects including but not limited to: depression, memory loss, and demyelinating diseases like multiple sclerosis and Alzheimer's.
Estrogen is a well known neuroprotective agent. However, as any male who has felt the sting of an aromatizing steroid can tell you, no man wants to be pumping himself full of estrogen. And there is no reason to; recent research has shown that certain androgens not only have neuroprotective effects comparable to estrogen, but actually stimulate myelin regeneration. Indeed, the androgen receptor has other functions besides being capable of adding slabs of muscle to the body, it adds myelin to our neurons! This myelin stimulating effect likely has a part to play in the “NZT48? feeling in regards to memory, concentration, and sex drive that many users report when using testosterone; the CNS is firing more smoothly and the neurons in your brain are sending electro-chemical signals at a superior rate.
Researchers have found that 5a-dihydrotestosterone (DHT) has the same capability of myelin regeneration as testosterone while 17a-methyl-testosterone and epitestosterone have a weaker capacity for myelin regeneration. The most interesting finding was that Trestolone (7a-methyl-19-nortestosterone) which recently hit the market showed capability of myelin regeneration comparable to testosterone and 5a-DHT. Trestolone just gets better and better; it is 10x as potent as testosterone, has no action in the prostate, and it is capable of myelin regeneration. Although data on its ability to aromatize is not very concrete, in vitro testing shows Trestolone to aromatize significantly more than Nandrolone, but less than Testosterone.
We sometimes forget the wide range of physiological effects the androgen receptor produces in our bodies. The androgen receptor is not limited to muscle tissue–it is expressed in many organs. It is expressed in our brains where it plays a role in sexual function and our CNS where it plays a role in physical strength. These neuronal androgen receptors help protect our neurons from myelin loss; improving our mood, sex drive, strength, and preventing demyelinating diseases. Check for yourself; see if you notice a little extra brain power next time you are on a cycle of Trestolone or Testosterone.
Hussain R. et al. The neural androgen receptor: a therapeutic target for myelin repair in chronic demyelination. Brain: A Journal of Neurology.Hammond J. et al. Testosterone-mediated neuroprotection through the androgen receptor in human primary neurons. Journal of Neurochemistry. Tags: Androgen Receptor, Myelin, testosterone, Trestolone